Rescued dogs, left to right: Oprah, Stedman and Gayle

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Weeks later, the rescued dogs are steadily making progress. "They're doing extremely well," Bill says.

Even if they've been living in one place for years, most of the dogs that come from puppy mills have never been named. That's one of the first things Bill and the volunteers at Main Line Animal Rescue do.

Bill says several of the dogs he and Lisa rescued were named in honor of their appearance on The Oprah Winfrey Show. "We have a 'Gayle' and we have an 'Oprah' and we have a 'Stedman,'" he says.

"Gayle" (pictured, on the right) is a female cocker, "Stedman" (middle) is a puppy with cauliflower ear, and "Oprah" (left) is a pug with a white chin. "Oh, my God, she has my eyes!" Oprah says.