Ellen Pompeo

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Ellen Pompeo, a.k.a. Dr. Meredith Grey, says even she doesn't know who Meredith picks! "That's the one reason I can't wait to get back to work," she says. "I'm really happy to be on vacation, but I'm sort of anxious to get back because I want to read what happens!"

In the series' first episode, Ellen's character falls for Dr. Shepherd (nicknamed "McDreamy" by her fellow interns) and continues to have feelings for him...even after his estranged wife joins the hospital staff. Meredith's romance with the veterinarian develops after things with her true love seem hopeless.

If Ellen was in Meredith's scrubs and had to decide between the two doctors, what would she do? "Well, you have to follow your heart," she says.