To many Oprah Show viewers, Bob Greene is synonymous with living a healthy lifestyle. Over the course of his 50 appearances on The Oprah Show, he has issued intense weight loss challenges, battled obesity in Mississippi, helped women across the country look and feel 20 years younger and essentially revolutionized the way many think about health.

Look back at Bob's past Oprah Show appearances   

But to Oprah, Bob is more than just a trainer and fitness guru. "You've been a great friend to me, really," Oprah says. "This guy has changed my life—affected my life—more than any other person on the planet."

Now, in his final Oprah Show appearance, Bob is back to change more lives with his expert advice, simple weight loss strategies and signature no-nonsense style.

Three questions everyone should ask themselves before trying to lose weight


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