Weight Loss All-Stars

Nancy
Current Weight: 173 pounds
Total Weight Loss: 530 pounds

For more than 12 years, Nancy rarely left her apartment. At her heaviest, she weighed more than 700 pounds and says she was too embarrassed to face the world. "I was in four walls in a very small space, and this was my world," she says. "It was my tomb."

At one point, Nancy says she realized she hadn't left her apartment in almost three years. Even life inside her small apartment became difficult when she hit her peak weight. "I would get winded just walking to the bathroom," she says. "As I was eating, I was thinking, 'You out-of-control slob. Why don't you have the ability to stop yourself?' I thought I was going to die. I never thought I'd claw my way out of it."

After years of being overweight, Nancy did claw her way out. Without diet pills or weight loss surgery, she lost a staggering 530 pounds! "All of us who struggle [to lose] 10 pounds, 5 pounds or 50 pounds, let Nancy be your 'she-ro' from this day forward," Oprah says.