It's been two years since Madeleine disappeared, and the McCanns are joining Oprah for their first interview in the United States. Though a good amount of time has passed, Kate says their search is as determined as ever. "We're still going, and we're working really hard," she says. "We have our better days and our not-so-good days, but we're persevering and we're pressing on."

See what Madeleine would look like today.

Anniversaries aren't necessarily harder, Kate says, but they are a reminder of just how much they've missed. "I can't believe it's been two years since I've seen Madeleine—that she's had two years without being with her family where she should be," she says.

Kate reflects on Madeleine's personality Watch


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