Clockwise from top left: James Denton, Ricardo Chavira, Josh Henderson and Doug Savant

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Desperate Housewives's Felicity Huffman has received awards for her outstanding acting and has even worked as Tina Turner's back-up singer. What's next? Her new book, A Practical Handbook for the Boyfriend, co-written with her friend Patricia Wolff.

"It was a culmination of a 20-year conversation with my best friend kind of going, 'Can't guys figure it out? Come on, get a clue,'" Felicity says.

Felicity took cameras behind the scenes on Wisteria Lane to ask probing questions of some of her male co-stars—James Denton, Doug Savant, Ricardo Chavira and Josh Henderson.

Felicity: So are all women crazy?
James: Oh, sure. Absolutely.

Felicity: So you grew up in a house full of women, right?
Ricardo: Yeah, a family full of women.
Felicity: So do you feel like you know women?
Ricardo: I know enough about women to know that I don't want to know any more.

Felicity: What does it take to make a man happy?
Doug: Sex, pretty much.
Felicity: And what does it take to make women happy?
Doug: God only knows.

Felicity: So you're single, right?
Josh: Yes. I get more and more confused it seems the more girls I date. I feel like they can just switch moods all of a sudden and you never know what you're going to get.