Tom Cruise

Photo: George Burns/Harpo Studios

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As the theme music to his 1996 blockbuster Mission: Impossible blasts from the speakers, Tom Cruise walks out and greets Oprah with a hug. Since his first Oprah Show appearance in 1988—"You looked like you were 10!" Oprah tells him—Tom has been on the show 12 times.

"Each time, I knew coming to Chicago that I was going to see a loving friend—and a friend who just happened to have a classroom of millions," Tom says. "For a quarter of a century, Oprah, you have quoted Glinda the Good Witch [from The Wizard of Oz]: 'You always had the power.' And that is the message you have brought into our lives."

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