Oprah on Marathons: About the 22nd Mile, You Start Calling on Jesus

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After a 2003 show, one audience member asked Oprah whether she planned to run another marathon, and she explained that she couldn't because of a knee injury. However, she noted, hip-hop artist Sean "P. Diddy" Combs would be stepping up to run the New York City Marathon, intent on beating Oprah's finish time.

Find out how Oprah feels about P. Diddy's challenge—and what she says everyone goes through a few miles from the finish line.