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According to Michael's autopsy, a lethal level of the powerful anesthetic propofol and another sedative caused his death. Lisa Marie says she didn't suspect Michael had a drug problem during their marriage, though she does recall one incident that gave her pause.

While rehearsing in New York for an HBO special in December 1995, Michael collapsed onstage and was rushed to the hospital. "I couldn't tell what was happening," Lisa Marie says. "Dehydration. Low blood pressure. Exhaustion. A virus."

"What did your gut tell you?" Oprah asks. "You thought there was some drug use?"

"Yes," she says.

Lisa Marie also recalls times when she would pick Michael up from a certain doctor's office, and he would not be coherent. Looking back, she says these behaviors were suspicious, but at the time, she didn't push the issue.

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