In 2006, Oprah issued her Pay It Forward Challenge. She gave 314 people in the studio audience $1,000 each, and then asked them to spend their $1,000 on a complete stranger. The jaw-dropping results made this Oprah's favorite giveaway ever!

One of the biggest givers was Minnie, a woman from Centralia, Illinois, who raised more than $70,000 for John Newcomb—a father of nine suffering from a deadly brain tumor.

Minnie's $1,000 multiplied with the help of friends and strangers, and their collective efforts helped pay John's hospital bills, buy groceries and send his oldest son to college. John's entire family surprised Minnie to say thank you in person.

Watch how Minnie made a big difference to John's family.

Then, another miracle happened just in time—a doctor who was watching The Oprah Show called and offered to remove John's brain tumor at no charge. 

Shortly after, John had another health setback when he suffered a stroke. Unable to continue working as a plumber, John has enrolled in college and one day hopes to earn a business degree. John says after all that Minnie did for him, he's not about to give up. "Minnie didn't have to help me," he says. "I don't think that I thanked Minnie the right way. Without you, I wouldn't be here."


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