antidepressants

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Mistaken Belief #4: Antidepressants will fix the problem

The Truth—SSRIs were a game changer when they came to market in the 1980s, and there are many other types of meds available (tricyclics, MAOIs, SNRIs), but none offers a one-size-fits-all fix. Why? "We don't really know how to match patient to treatment very well," says Gotlib. "With cancer, researchers are looking at genotypes to predict response to specific treatments. We're not there yet with psychiatric disorders." At the moment, depression treatment typically involves a complicated, potentially lengthy process of figuring out the right medication, type of therapy or combination of the two, then waiting to see if it works. Even after that, "[only] 65 percent of people will get better," says Gotlib.