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Antidepressant Anti-Inflammatories
There's an intriguing connection between bodily inflammation and emotional deflation: Studies reveal that taking the anti-inflammatory celecoxib (Celebrex) can further alleviate symptoms for people on antidepressants. Other research suggests that consuming omega-3 fatty acids may decrease inflammation while improving mood.

Brain inflammation can be 30 percent higher in clinically depressed patients, according to a 2015 study, and even mild depression is linked to elevated levels of pro-inflammatory markers. K. Ranga Krishnan, MD, dean of Rush Medical College, notes that people with psoriasis, an inflammatory skin disease, often have depression—and when they're treated with anti-inflammatories, their mood typically improves along with their skin. Based on these and other findings, researchers hope to develop anti-inflammatory medication that targets depression.