Anthony Hopkins as Hannibal Lecter in Silence of the Lambs

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Hannibal Lecter, Silence of the Lambs
First of all, he eats people. That's plain deplorable. And though he's only on the big screen for 16 minutes, Anthony Hopkins triggers plenty of nightmares with his bone-chilling glare and that infamous "fava beans and a nice Chianti" line. Plus, before he was an incarcerated cannibalistic serial killer, he was a psychiatrist. The bad guys who can get inside your head are the creepiest—no, er, bones about it.