Cameron lost her father when she had only three weeks left of filming My Sister's Keeper, but she says she's still not sure if the experience influenced her performance. "I don't know if I could say even now, a year later, if it hurt me or helped me—if I was present with it or if I was completely in shock," she says. 

Oprah calls My Sister's Keeper a three-hankie film, but Cameron says it's more than just a tearjerker. "It's just as much about celebrating life as it is about the tears," she says. 

Kelly Ripa chimes in to the Oprah Fridays panel!

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