Gayle's cake quest takes her from New York City to Nashville, Oprah's hometown! She heads straight to Tennessee T-Cakes, a sweet shop known for their "ultimate Southern confections."

Inside the shop, bakers serve up bite-sized cakes in four flavors— original, chocolate truffle, luscious lemon and key lime. Each batch is baked for exactly 14 minutes, and then the cakes are finished off with a light sprinkle of powdered sugar.

Owner Frances Barkley reveals the secret ingredients that make her T-Cakes so special—flour, butter, sugar, eggs and vanilla. "What's so unusual about that?" Gayle asks.

"It's the portions and the brands of things that I use. That makes a big difference," Frances says. "Everything is top of the line in this T-Cake."