important for us to -- survived but dead elsewhere the cause of genetic disorders I was intrigued in reading it genetic -- the name of this. Most recent book He has of -- his -- Indian term blues measurement that's about. -- and albums that the CD that double the world really. Yes actually now if if it's the book of internship. Yeah that we're learning to play god the community too young doctor you do learn to play god sometimes unfortunately. What me Texas -- of those teams but the general topic going to get into it was genetic grounds and -- -- a little bit about how we define genetic disorders. And and to a disconnect we still have with the public about genes so let's sort of debate very basic. Concept and -- by the -- thank you. -- -- -- -- genetic disorder -- genetic disorder . Is the condition that's caused by alterations. In him the genome. Panic it can be. Has. Has clear as. A single gene mutation causing something like sickle cell policies are Tay Sachs disease . Or. Disorders that have a genetic component. Which. You know require some environmental. -- in order to manifest themselves. For instance diabetes. And so actually when you think about it virtually every disease has a genetic component in this a genetic disorder . I'm I'm often asked by. Patience of mine are gonna have to about her tree but it's genetic . And -- -- -- -- affairs -- had a much about operated on. -- -- -- -- yes there's a genetic element DP that made you more likely to get whatever problems occurred because the leakage and now. But I think for most people out there there are sort of thinking about it as a very clear on social dominant pattern which means if you know what might that my parents have I have 12 -- getting it there it. We are at a but it ailment a leader in this program. Where to that is case but for right now if on average. What percentage of kids were born with genetic abnormalities had a parent without. Well actually that number is is pretty low only about 45%. Of of congenital -- formations. Have have a purely genetic basis. A little more for chromosomal abnormalities like -- from. Suits the total somewhere between ten and 20% of of kids with congenital -- formations with birth defects have that as a result of some. Clearly genetic . Abnormality. Something that's passed along from their parent to themselves. I think there's a little bit of a disc I just because when people say genetic . And you assume it's inherited thing but all of really means is at its heart it's it's because of something in the genes are taken -- a spontaneous meet mutation in the gene and that's a genetic . Order rate has not passed on your parents right and and so there we have to distinguish between genetic which just means -- change -- -- and hereditary. Which means really passed on from here if you could just for everybody can differentiate chromosomal abnormality from a genetic -- don't I don't think the most. Folks who probably -- those together. Right so chromosomal abnormality is one in which there's either too much or too little genetic material and make him the most common that we see in humans is dance. Where there's an extra copy of chromosome two point one. I genetic disorder . A -- is an abnormality often and -- in a single team the genes they're 20000 genes that make up our. --