Crossing your legs, wearing underwear made of synthetic fabrics that are less breathable than cotton and sitting for long periods can all cause sweating in the crotch and seat areas. Since the skin near the vagina is particularly thin and sensitive, avoid masking odor with perfume or using wipes that contain antibacterial agents, hydroxy acids or acne medication (like salicylic acid or benzoyl peroxide). Try fragrance-free towelettes or opt for a version meant for babies. And be careful to wipe only the skin around the vagina—neither the labia nor the inside of the vagina perspires. After a shower or before putting on underwear, O'Brien suggests, applying Zeasorb-AF (an antifungal powder that guards against rashes that can break out on warm, damp skin) or baby powder to help absorb moisture throughout the day.