A: I love the look of mature hands; they seem to have earned the right to wear good jewelry. But there's lots you can do if you want youthful hands, says Deborah Sarnoff, MD, clinical professor of dermatology at New York University Medical Center. Hyperpigmentation (brown spots) can be eradicated with one treatment of a pigment-specific laser, like the Q-switched ruby or alexandrite. (A bleaching cream takes longer to work but will fade spots in about six weeks.) At night, apply a vitamin A prescription cream like Renova, or an over-the-counter retinol cream. Always remember to use an SPF 30 sunscreen on your hands to prevent new spots. If veins are your bugaboo, they can be diminished by injections of a filler like Radiesse or Sculptra.
Keep in mind: Wear cotton-lined or rubber gloves when you're working around the house and leather gloves when you're outside. And moisturize like crazy.