Oprah
Photo: George Burns
What I know for sure is that if you were going to buy only one issue, ever, of O, this would be the one. Learning to trust your instincts, using your intuitive sense of what's best for you, is paramount for any lasting success. I've trusted the still, small voice of intuition my entire life. And the only time I've made mistakes is when I didn't listen.

It's really more of a feeling than a voice—a whispery sensation that pulsates just beneath the surface of your being. All animals have it. We're the only creatures that deny and ignore it.

A while back, Bob Greene and I were walking with my dogs around the pond at my home in California. The weather was damp and misty, and I was concerned that it was too cold for the dogs to go in the water. But Bob said, "Don't worry—they're dogs. They're not going to stay in the water if it's too cold. Animals don't deliberately cause themselves discomfort the way people do."

How many times have you gone against your gut, only to find yourself at odds with the natural flow of things? We all get caught up in the business of doing, and sometimes lose our place in the flow. But the more we can tune in to our intuition, the better off we are. I believe it's how God speaks to us.

For all the major moves in my life—to Baltimore, to Chicago, to own my show, and to end it—I've trusted my instincts. I take in all the information I can gather. I listen to proposals, ideas, and advice. Then I go with my gut, what my heart feels most strongly.

And I often tell friends: When you don't know what to do, do nothing. Get quiet so you can hear the still, small voice—your inner GPS guiding you to true North.

Follow Your Intuition
From the August 2011 issue of O, The Oprah Magazine.