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Usually we think about this question in terms of our jobs or our professional success or failure. But take a deeper look, says Spencer. "What if you asked yourself, Am I supposed to have a greater love? Am I supposed to be following a greater passion? Am I supposed to be helping people?"

Leigh Newman is the deputy editor of Oprah.com and the author of Still Points North: One Alaskan Childhood, One Grown-Up World, One Long Journey Home.

Next: How to find the kind of joy that lasts