Bono's New Job

If you are interested in helping the people of Africa, there are many ways you can make a difference. "You should choose based upon what speaks to your heart so that it's not just a check that you're writing. That you literally are making a spiritual connection, and the spiritual connection will be felt wherever it is you're sending the money to," Oprah says.

Oprah says she knows of two great organizations. One is an organization called Women for Women International. Through Women for Women International, you can sponsor a woman in another country and help her find a better life. "They have people over wherever the country is, whether it's Ecuador or Africa or, you know, China, and they have a support system that helps those women build businesses," Oprah says. For more information, visit Womenforwomen.org.

Another organization to consider is Heifer International, a group working to end world hunger and poverty while caring for the earth. Through the organization, you can donate livestock and other items that help families provide for themselves. "You can go and you can buy a goat, you can buy two goats, you can buy a sheep, you can buy a pig. You can buy a whole farm," Oprah says. For more information, visit Heifer.org.

But Oprah doesn't like to just give money, she likes to get involved. It's only natural that two more organizations are close to her heart—the Oprah Winfrey Leadership Academy Foundation and Oprah's Angel Network.