Christina Applegate and Oprah

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Christina made the dramatic decision to have a bilateral mastectomy. "It came on really fast. It was one of those things that I woke up and it felt so right," she says. "It just seemed like, 'I don't want to have to deal with this again. I don't want to keep putting that stuff in my body. I just want to be done with this.' ... I was just going to let them go."

Before she went in for her surgery, Christina says she staged her first—and last—nude photo shoot. "I made sure that I have close-up photographs of them from every angle so I can kind of remember them," she says.

Christina's tears finally spilled over the day she met her surgeon. "I met with my doctor, and I told him that was my decision," she says. "He brought the surgeon in, and it was like it was the floodgates just opened up and I lost it."

In July 2008, Christina went through with the surgery, which has left physical and emotional scars. "It can be very painful," she says. "It's also a part of you that's gone, so you go through a grieving process and a mourning process."
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