If you've fallen off the fitness wagon, resolve to get fit in 2009. Oprah & Friends hosts Bob Greene, Gayle King, Peter Walsh and Dr. Mehmet Oz talk about getting in shape, eating right and losing the weight for good. And Oprah shares her personal weight loss journey.

Plus, hear Bob's four life lessons on fitness—practical guidelines to achieve the body you want in 2009.

Hour 1
It's an intimate conversation only two best friends can have—Oprah and Gayle have a heart-to-heart discussion about Oprah's recent weight gain, the misdiagnoses of her thyroid disease and her candid confession in the January 2009 issue of O, The Oprah Magazine. Plus, Gayle and Bob talk about how to get back on the fitness wagon.

Hour 2
As a record-setting long-distance runner, fitness coach and motivational speaker, Stu Mittleman can help you achieve your fitness goals. He talks with Dr. Oz about how to maximize your fitness potential, become more physically active and eat better.

Hour 3
Being fit isn't just about eating right and exercising, it's also about making sure your entire life is clutter-free. Peter shares weight loss advice from his book Does This Clutter Make My Butt Look Fat? and talks about how to get your weight under control to live a healthier life. Plus, he talks with fitness expert Jim Karas about how to stop creating excuses and start making fitness a priority.

Hour 4
Every day is a new chance to turn your life around. Last year, Debra Flinn, who was overweight and unhappy, took that chance when she decided to walk from Cape Coral, Florida, to Chicago to meet her idol—Oprah! Debra talks with Bob about her motivation, her struggles with her weight and her life-changing journey.