December 2008
| 12/30/08 | Singer/Songwriter Ne-Yo (repeat) |
| 12/29/08 | Lance Armstrong (repeat) |
| 12/26/08 | Actress/Singer Janet Jackson (repeat) |
| 12/25/08 | Producer and Songwriter David Foster (repeat) |
| 12/24/08 | Singer Seal (repeat) |
| 12/23/08 | Singer Tony Bennett (repeat) |
| 12/22/08 | The World According to Gayle |
| 12/19/08 | Singer/Songwriter Melissa Etheridge |
| 12/18/08 | Singer/Songwriter John Legend |
| 12/17/08 | Comedian Denis Leary (repeat) |
| 12/16/08 | Actress Diahann Carroll (repeat) |
| 12/15/08 | The World According to Gayle |
| 12/12/08 | Sprinkles Cupcakes |
| 12/11/08 | Illinois Governor Arrested |
| 12/10/08 | Stuff White People Like (repeat) |
| 12/09/08 | Kiss My Math (repeat) |
| 12/08/08 | The World According to Gayle |
| 12/05/08 | Rapper/Songwriter T.I. |
| 12/04/08 | The Secret Pleasures of Menopause (repeat) |
| 12/03/08 | Supermodel Iman (repeat) |
| 12/02/08 | Utmost Living (repeat) |
| 12/01/08 | The World According to Gayle |
November 2008
| 11/28/08 | Broadway Star Rita Rudner (repeat) |
| Comedian Margaret Cho (repeat) | |
| 11/27/08 | Poet/Author Dr. Maya Angelou (repeat) |
| 11/26/08 | Comedian Denis Leary |
| 11/25/08 | The Power of Jazz (repeat) |
| 11/24/08 | The World According to Gayle |
| 11/21/08 | Author Jena Pincott (repeat) |
| Why Do Men Cheat? (repeat) | |
| 11/20/08 | Sarah Ferguson (repeat) |
| Fitness Expert Chalene Johnson (repeat) | |
| 11/19/08 | Singer Seal |
| 11/18/08 | The World According to Gayle |
| 11/17/08 | The Obama Administration |
| 11/14/08 | Actor Rob Fagin |
| 11/13/08 | Designer Kenneth Cole |
| 11/12/08 | The World According to Gayle |
| 11/11/08 | How to Embrace Change |
| 11/10/08 | Flat Belly Diet! |
| 11/07/08 | Chef Govind Armstrong |
| 11/06/08 | Producer and Songwriter David Foster |
| 11/05/08 | Election Results |
| 11/04/08 | A Historic Presidential Election |
| 11/03/08 | Poet/Author Dr. Maya Angelou |
October 2008
| 10/31/08 | Building a Green Economy |
| 10/30/08 | Life Coach Martha Beck |
| 10/29/08 | San Francisco Treats |
| 10/28/08 | Financial Expert Suze Orman |
| 10/27/08 | San Francisco Mayor Gavin Newsom |
| 10/24/08 | Supermodel Iman |
| 10/23/08 | O-White House Leadership Project |
| 10/22/08 | Singer/Songwriter Sarah McLachlan |
| 10/21/08 | The World According to Gayle |
| 10/20/08 | Fitness Expert Chalene Johnson |
| 10/17/08 | The Secret Pleasures of Menopause |
| 10/16/08 | The Final Presidential Debate |
| 10/15/08 | Politics in America |
| 10/14/08 | The World According to Gayle |
| 10/13/08 | Sarah Ferguson |
| 10/10/08 | Author Jena Pincott |
| 10/09/08 | Singer and Actress Jennifer Hudson |
| 10/08/08 | After the Presidential Debate |
| 10/07/08 | The World According to Gayle |
| 10/06/08 | Actress Diahann Carroll |
| 10/03/08 | The Vice Presidential Debate |
| 10/02/08 | Singer Robin Thicke |
| 10/01/08 | Why Do Men Cheat? |
September 2008
| 09/30/08 | Breast Cancer Parties |
| 09/29/08 | Debating the Presidential Debate |
| 09/26/08 | Author Nicholas Sparks (repeat) |
| 09/25/08 | An Anniversary Celebration! |
| 09/24/08 | Director Spike Lee |
| 09/23/08 | The Power of Jazz (repeat) |
| 09/22/08 | How to Win a Political Argument |
| 09/19/08 | Laughing with Sherrod Small |
| 09/18/08 | Fred and Kim Goldman |
| 09/17/08 | Overcoming Sexual Abuse |
| 09/16/08 | The ServiceNation Presidential Forum |
| 09/15/08 | Singer Tony Bennett |
| 09/12/08 | Olympians Lisa Leslie and Jennie Finch |
| 09/11/08 | Olympians Kobe Bryant and Shawn Johnson |
| 09/10/08 | Olympians Cullen Jones and Dara Torres |
| 09/09/08 | Olympians Natalie Coughlin and Michael Phelps |
| 09/08/08 | Chicago Mayor Richard M. Daley |
| 09/05/08 | Common Social Taboos |
| 09/04/08 | The Power of Jazz |
| 09/03/08 | Getting Good Service at Restaurants |
| 09/02/08 | Broadway Star Rita Rudner (repeat) |
| 09/01/08 | Hurricane Gustav |
August 2008
| 08/29/08 | Oprah and Gayle on the Convention |
| 08/28/08 | Will.i.am and James Clyburn |
| 08/27/08 | Political Strategist Donna Brazile |
| 08/26/08 | Rachel Maddow and John Legend |
| 08/25/08 | Michelle Obama |
| 08/22/08 | Federal Air Marshals (repeat) |
| 08/21/08 | Shred America (repeat) |
| 08/20/08 | The Black List |
| 08/19/08 | How to Become a Gentleman |
| 08/18/08 | Author Nicholas Sparks |
| 08/15/08 | Comedian Margaret Cho |
| 08/14/08 | Fall Fashion Advice |
| 08/13/08 | Kiss My Math |
| 08/12/08 | Stuff White People Like |
| 08/11/08 | The World According to Gayle |
| 08/08/08 | Reverend Run and Justine Simmons |
| 08/07/08 | "What to Eat When You Need a Fix" |
| 08/06/08 | Celebrating Esquire's 75th Anniversary |
| 08/05/08 | Peach Day! |
| 08/04/08 | "Now What Do I Do?" |
| 08/01/08 | Winning the Lottery |
July 2008
| 07/31/08 | Tips for Dining Out |
| 07/30/08 | Gymnast Dominique Dawes |
| 07/29/08 | The World According to Gayle |
| 07/28/08 | Humor in the Church |
| 07/25/08 | Freelance Producer Patrick Riley |
| 07/24/08 | Utmost Living |
| 07/23/08 | CNN's Black in America |
| 07/22/08 | The World According to Gayle |
| 07/21/08 | Surviving an Intrusion |
| 07/18/08 | Art For Life |
| 07/17/08 | Shred America |
| 07/16/08 | Single and Happy |
| 07/15/08 | The World According to Gayle |
| 07/14/08 | Journalist Rachel Maddow |
| 07/11/08 | TV Host Al Roker |
| 07/10/08 | Creative Ways to Say No |
| 07/09/08 | Broadway Star Rita Rudner |
| 07/08/08 | The World According to Gayle (repeat) |
| 07/07/08 | Antonio "L.A." Reid (repeat) |
| 07/04/08 | Singer/Songwriter Seal (repeat) |
| 07/03/08 | Kenneth "Babyface" Edmonds (repeat) |
| 07/02/08 | Actress/Singer Janet Jackson (repeat) |
| 07/01/08 | Singer Chrisette Michele (repeat) |
June 2008
| 06/30/08 | Singer/Actress Jill Scott (repeat) |
| 06/27/08 | Medical Myths (repeat) |
| Tennis Pro Martina Navratilova (repeat) | |
| 06/26/08 | Navigating the Workplace (repeat) |
| Surviving a Divorce (repeat) | |
| 06/25/08 | 8 Simple Rules for Marrying My Daughter |
| Actor Evan Handler | |
| 06/24/08 | Accepting Gay Children |
| 06/23/08 | "A Slice of Brooklyn Pizza Tour" |
| 06/20/08 | Comedian Mike Myers |
| 06/19/08 | Lance Armstrong |
| 06/18/08 | The World According to Gayle |
| 06/17/08 | Hip-Hop Mogul Jermaine Dupri (repeat) |
| 06/16/08 | Singer Alicia Keys (repeat) |
| 06/13/08 | Equal Parenting |
| 06/12/08 | Hip-Hop Singer Will.i.am |
| 06/11/08 | Medical Myths |
| 06/10/08 | Actress Jenifer Lewis on Broadway |
| 06/09/08 | Hamburger America |
| 06/06/08 | The Presidential Election |
| 06/05/08 | Katie Lee Joel |
| 06/04/08 | Television Star Hill Harper |
| 06/03/08 | The World According to Gayle |
| 06/02/08 | A Website for Women (repeat) |
| Writer Simon Doonan (repeat) |
May 2008
| 05/15/08 | Singer BeBe Winans (repeat) |
| 05/14/08 | Navigating the Workplace |
| 05/13/08 | The World According to Gayle |
| 05/12/08 | 8 Simple Rules for Marrying My Daughter |
| 05/09/08 | Writer Simon Doonan |
| 05/08/08 | A Website for Women |
| 05/07/08 | Surviving a Divorce |
| 05/06/08 | The World According to Gayle |
| 05/05/08 | Actor Evan Handler |
| 05/02/08 | Supermodel Christy Turlington Burns |
| 05/01/08 | Former NBA Star Allan Houston |
April 2008
| 04/30/08 | Singer Mariah Carey |
| 04/29/08 | NBA Star Charles Barkley |
| 04/28/08 | A New Broadway Star |
| 04/25/08 | Actress Janine Turner |
| 04/24/08 | Singer Patti Austin |
| 04/23/08 | Thoughts on the Presidential Election |
| 04/22/08 | The World According to Gayle |
| 04/21/08 | It's Hip Hop, Baby! |
| 04/18/08 | Designer Donna Karan |
| 04/17/08 | Men Can Stop Rape |
| 04/16/08 | Actress Kerry Washington |
| 04/15/08 | Actress Rosario Dawson |
| 04/14/08 | Actress Jane Fonda on V-Day |
| 04/11/08 | Mama Rock's Rules |
| 04/10/08 | TV Journalist Lesley Stahl |
| 04/09/08 | Civility in America |
| 04/08/08 | Inspirational Stories |
| 04/07/08 | The World According to Gayle |
| 04/04/08 | Preventing School Shootings |
| 04/03/08 | Professional Boxer Laila Ali |
| 04/02/08 | CNN's Black in America |
| 04/01/08 | The World According to Gayle |
March 2008
| 03/31/08 | The 50 Million Pound Challenge |
| 03/28/08 | The Truth About Why Women Lie |
| 03/27/08 | Rap Artist Master P |
| 03/26/08 | Actress Phylicia Rashad |
| 03/25/08 | Deb Gotti Is Moving On |
| 03/24/08 | The World According to Gayle |
| 03/21/08 | Singer/Songwriter Ne-Yo |
| 03/20/08 | Actor and Former NBA Star Rick Fox |
| 03/19/08 | Actress Valerie Bertinelli |
| 03/18/08 | The World According to Gayle |
| 03/17/08 | More with Comedian Sherrod Small |
| 03/14/08 | Oprah's Big Give Judge Malaak Compton-Rock |
| 03/13/08 | Antonio "L.A." Reid (repeat) |
| 03/12/08 | Politics and Scandals |
| 03/11/08 | The World According to Gayle |
| 03/10/08 | Suzy Welch on Bad Bosses (repeat) |
| 03/07/08 | Chef Jamie Oliver |
| 03/06/08 | Coach C. Vivian Stringer |
| 03/05/08 | Living a Green Life |
| 03/04/08 | The World According to Gayle |
| 03/03/08 | Oprah's Big Give Executive Producer |
February 2008
| 02/29/08 | Oprah's Big Give Host Nate Berkus |
| 02/28/08 | Singer Ashanti |
| 02/27/08 | Heart Transplant Recipient Kelly Perkins |
| 02/26/08 | The World According to Gayle |
| 02/25/08 | Beth Holloway (repeat) |
| 02/22/08 | Style Expert Tim Gunn (repeat) |
| 02/21/08 | Antonio "L.A." Reid |
| 02/20/08 | The World According to Gayle |
| 02/19/08 | E-mail Detox |
| 02/18/08 | NFL Star Michael Strahan |
| 02/15/08 | Playwright Eve Ensler |
| 02/14/08 | Suze Orman on Women & Money |
| 02/13/08 | The World According to Gayle |
| 02/12/08 | Fashion Designer Isaac Mizrahi |
| 02/11/08 | Iron Chef Cat Cora |
| 02/08/08 | Gayle and Kirby's Health Retreat |
| 02/07/08 | Actress Ali Wentworth |
| 02/06/08 | Super Tuesday Recap |
| 02/05/08 | The World According to Gayle |
| 02/04/08 | Hearst Magazines' Cathie Black (repeat) |
| 02/01/08 | Party Planner Colin Cowie |
January 2008
| 01/31/08 | Living a Healthier Life |
| 01/30/08 | Finding Love |
| 01/29/08 | The World According to Gayle |
| 01/28/08 | Singer Alicia Keys (repeat) |
| 01/25/08 | Singer Chaka Khan |
| 01/24/08 | Style Expert Charla Krupp |
| 01/23/08 | Style Expert Tim Gunn |
| 01/22/08 | Beth Holloway |
| 01/21/08 | Babies and Politics |
| 01/18/08 | Singer BeBe Winans |
| 01/17/08 | Actress Diane Keaton |
| 01/16/08 | Body Drama (repeat) |
| 01/15/08 | The World According to Gayle |
| 01/14/08 | Flocabulary |
| 01/11/08 | Best Week Ever's Sherrod Small |
| 01/10/08 | Political Engagement Among College Students |
| 01/09/08 | Eat This, Not That |
| 01/08/08 | The World According to Gayle |
| 01/07/08 | Body Drama |
| 01/04/08 | Sexual Harassment in the Workplace |
| 01/03/08 | The World According to Gayle |
| 01/02/08 | The Anniversary Celebration Continues (repeat) |
| 01/01/08 | Happy First Anniversary! (repeat) |
