Oprah: Where Are They Now? unlocks the The Oprah Winfrey Show vault and takes a look back at '90s newsmaker Mary Jo Buttafuoco and the 28-year old addicted to plastic surgery. Tune-in for updates from these guests and more!

Dennis Rodman reveals his biggest regret. Nadya Suleman, known as Octomom, shares why she agreed to star in an adult movie and gives a tour inside her new home. Then, Gennifer Flowers talks about her political sex scandal 21 years later.

An aspiring TV anchorwoman is brutally murdered in her home, police zero in on two suspects, both men she dated. In another story, the parents of a young woman who was raped and killed take matters into their own hands to solve the case.

Even after years of marriage, most couples still have some secrets left, but probably not the kind one husband kept from his wife. One day she looked her husband in the eye, and she had no idea who was looking back.

A man comes into the ER with an unfortunate reaction after taking performance-enhancing drugs. An ER nurse treats her dwarf costume-wearing patient who fell while performing at a party.

An ex-military man's face is damaged after a visit to a dermatologist in one of the strangest burns his nurse has ever seen. A first year doctor finds himself in over his head while working in the severely understaffed ER.

A trauma surgeon flies into action to save a man shot in the chest. The ER staff is stunned by a patient with a bizarre eating disorder - in his stomach they find nuts, bolts, and screws.

The ER rushes to treat a construction worker struck with hot tar melting his skin. A cyclist hit by a taxi tries to comfort his fiancée, hoping his wounds heal before their wedding. A young doctor finds love at the hospital.