After 3 days at the beach for Spring Break, 17 year-old Brittanee Drexel vanishes just moments after texting her boyfriend. When police track her cell phone to an isolated rural area, known for alligators and swamps, her family fears the worst.

When 17-year-old Kara Kopetsky doesn't come home from school one day, her family panics. Foul play is suspected and a series of unsettling clues surface. But the leads grow cold until a month later when another local teenage girl goes missing.

After six months in the Mojave Desert in 2004, following the custody loss of her children in Texas, 30 year-old April Pitzer is ready to come clean and return home. But when her past comes back to haunt her, the young mother of two is nowhere to be found.

Twenty-two year old Bradyn Fuksa vanishes from his new apartment. When his car is found 700 miles away, Bradyn's parents feel their world turn upside down. But the surprises don't stop there as it's revealed that Bradyn has been guarding a dark secret.

A single mother takes an evening walk while chatting on her cell with her boyfriend. Suddenly, he hears her scream - begging someone not to take her. Police think she's been abducted - but by who? Eight months later, a potential suspect emerges.

Tanya Rider goes missing after her shift in a grocery store in Bellevue, Washington. Her husband Tom tries filing a missing person's report but is refused because police believe she left on her own. Police later zero in on Tom as their prime suspect.

Marina resort owners Liz and John Calvert live the good life. But when they discover money missing from their business account, they meet with their accountant. The next day, they're nowhere to be found. Does their associate know more than he claims?

After doing laundry at a local Laundromat, 28 year-old Niqui McCown disappears. Six years later, an anonymous tip to police connects a former colleague of Niqui's to an unsolved murder of a different woman. Detectives must see if the cases are connected.