Beauty queens - as American as apple pie, adored by little girls everywhere. But over the past few years it's little girls, rather than women, who have taken center stage. Who are these pint-sized princesses? And whose dreams are they really fulfilling?

Lisa Ling explores the disturbing underworld of domestic human sex trafficking in America - where it's estimated that as many as 300,000 underage girls born in the United States are bought and sold for sex every year.

Oprah visits the home of actor Neil Patrick Harris, his fiancé David Burtka and their 18-month old twins. In this TV exclusive, Neil and David talk candidly about coming out, their decision to have children and the pressures of life in Hollywood.

Oprah visits Michael Jackson's daughter Paris to see how she is doing nearly 3 years after her father's death. Then, after years of feud rumors, Oprah interviews rapper 50 Cent. They discuss how he has built his reportedly $100 million empire.

A professor from Miami and a graduate student from Texas, put their brains together for the chance to win $100,000! Is it normal to have a tattoo? Is it normal to have sex in public? Find out on the new game show "Are You Normal, America?"

A report on details into the search for Natalee Holloway, a U.S. teenager who disappeared on May 30, 2005 during a post-graduation trip in the Caribbean island of Aruba.