In 2001, Chandra Levy, a young political intern, vanished without a trace. One year later, her body was discovered in a Washington park. Today, her parents, Robert and Susan Levy, talk about their daughter's case, how they've coped and how they really feel about the man convicted of Chandra's murder.

Then, in 1985, Ryan White became a household name for being barred from his middle school when he contracted AIDS during a blood transfusion at age 13. Now, his mother, Jeanne, shows how she keeps her son's legacy alive. Plus, we hear from the young woman who found herself raising her nine special-needs siblings after their parents were murdered in their home in 2009.

On April 20, 1999, the world was shocked to the core when two teenage students shot and killed 12 classmates and one teacher at Columbine High School in Littleton, Colorado. Today, we hear from survivors Adam, Craig and Patrick about how they moved on from the tragedy.

Then, former heavyweight boxing champion of the world, Mike Tyson, is no stranger to the ups and downs that can come from fame and fortune. Having hit bottom, Mike has dramatically altered his life since his last Oprah Show appearance in 2009. From his home in Las Vegas, Mike talks about his new lifestyle as a happily married, committed father who dropped more than 100 pounds. Plus, America's number one reality TV couple, The Bachelorette's Trista Sutter and her husband, Ryan, update us on what life is like after 10 years of marriage and two kids.

Omarosa was known as reality TV's number one bad girl on the original season of The Apprentice. Now, in her first sit-down interview since the death of her fiancé, Oscar®-nominated actor Michael Clarke Duncan, a very emotional Omarosa reveals how she is coping with the sudden death of the love of her life, who passed away in September 2012 from respiratory failure.

Then, Paul Michael Glaser, who played Detective David Starsky on the popular '70s television series Starsky & Hutch, is widely known as an activist for AIDS prevention. In 1981, his wife, Elizabeth, contracted the disease from a blood transfusion and unknowingly passed it on to her children. Today, we look back on Elizabeth's 1991 interview with Oprah and catch up with Paul and his son, Jake.

Sinbad rose to fame in the early '90s as a stand-up comedian and actor, best known for his role as coach Walter Oakes on the hit TV series A Different World and for his popular HBO comedy specials. After 14 Oprah Show appearances, Sinbad is back, talking about his new band, his family and the greatest lessons he's learned over the past three decades.

Then, Olympic runner Marion Jones was once hailed as the fastest woman in the world and a hero to millions until she was found guilty of lying about using steroids and served six months in federal prison. Four years later, she talks about what life is like for her today. Plus, find out what she has to say about Lance Armstrong's recent doping confession to Oprah.

Plus, Sex and the City was a cultural phenomenon created by Candace Bushnell. Sixteen years later, find out about the new novel she is working on and why she prefers to stay away from the limelight.

Dennis Rodman was one of the most controversial and flamboyant superstars of the NBA. In the '90s, the notorious 6'8" professional basketball player was the number one rebounder on the court, but he was just as famous for his dyed hair, piercings, tattoos and press-grabbing antics—on and off the court. It's been 16 years since Dennis' appearance on The Oprah Show. Now, he reveals what his life is like today and discusses his most surprising recent project, writing a children's book.

Then, a medical first in 2009 made news around the world. A mother of six named Nadya Suleman gave birth to the world's longest-surviving octuplets. Overnight, Nadya, better known as the "Octomom," became the most controversial and scrutinized mother in America. Now, the octuplets are 4 years old, and Nadya reveals why she agreed to star in an adult movie.

Plus, more than two decades after her sex scandal broke, Gennifer Flowers shares what she thinks politicians can learn from her story.