Despite the death and destruction he experienced during the 2004 tsunami, Nate Berkus says he saw the best of humanity in Sri Lanka. Watch more of his 2005 interview and find out why Oprah says it's one she'll never forget.

If anyone's a true Tina Turner fan, it's Oprah! After making fans' wildest dreams come true for years, Oprah realized one of her own in 1997 when she went on tour with her idol. Find out how Oprah and Tina's road trip came about and why performing with Tina left Oprah "knee-shaking nervous."

Oprah says there's a reason people say that there's no life like a rockstar's life. Find out what she learned during her time on the road with Tina Turner in 1997.

In 1987, Forsyth County, Georgia, was known as a hotbed of racism. Not one single black person had lived there since World War I. Oprah decided to take her show on the road for a town hall meeting, but she says that before setting foot in Forsyth County, she knew she would be walking into a hostile environment. Look back at footage from that show and watch as Oprah reflects about being anxious during the taping.

In its 25 years on the air, The Oprah Show never backed down from tough conversations about race, and TV Guide chose Oprah's show in Forsyth County, Georgia, as the most significant. Back then, Forsyth County was known as a hotbed of racism. Not one single black person had lived there since World War I. Oprah took her show to Forsyth County for a town hall discussion on February 9, 1987.

The Oprah Winfrey Show was known for making dreams come true. On May 16, 1997, Oprah made her own wildest dream come true by hitting the stage with Tina Turner and performing with the music legend in Houston. That season, Oprah took The Oprah Show on the road for Tina's Wildest Dreams tour.

During the 2008 presidential campaign, rumors swirled that Oprah had snubbed Republican vice-presidential candidate Sarah Palin by not asking her to appear on The Oprah Show. On November 16, 2009, about a year after the former governor of Alaska lost her vice-presidential bid, she and Oprah met for the first time on Oprah's stage in a world-exclusive interview to talk about the campaign, her family and her future.

During the 2008 presidential campaign, rumors swirled that Oprah had snubbed Republican vice-presidential candidate Sarah Palin by not asking her to appear on The Oprah Show. Then, a year later, it was announced Oprah and Palin would sit down in a world-exclusive interview. Watch as Oprah reveals what really happened and why she received some of the worst hate mail of her career from the incident.

It's the moment TV Guide Magazine chose as number 10, but Oprah says it's in her personal top five. Watch as Oprah looks back on her 2006 interview with Nobel Peace Prize winner Elie Wiesel at the Auschwitz death camp in Poland.

Nobel Peace Prize winner Elie Wiesel is one of Oprah's all-time heroes. Watch as she shares why visiting Auschwitz with the Holocaust survivor was a "life-fulfilling moment" for her and why she was so proud of that show.