Oprah speaks one-on-one with two of the country's most powerful women: Facebook COO Sheryl Sandberg and Supreme Court Associate Justice Sonia Sotomayor.

John of God describes himself as a spiritual medium and says his body incorporates the spirits of deceased healers, which he calls entities, during his spiritual and physical surgeries. Watch as John of God tells Oprah how the entities come to him. Plus, John of God explains to Oprah why she felt faint in the healing center's main sanctuary.

Every year, people from around the world flock to Abadiania, Brazil, the remote village that's home to John of God's healing center, the Casa. Oprah traveled 6,000 miles to see John of God's controversial practices firsthand. Watch as she observes a shocking physical surgery and find out why she had to sit down.

Watch as Oprah and John of God sit beneath a mango tree in Brazil to discuss his gift. Plus, find out how Joao Teixeira de Faria, a tailor's son who never learned to read or write, became known around the world as John of God.

All the Americans Oprah met at John of God's spiritual center in Brazil told her they hoped he could perform a miracle for them. What happened after they returned to their hometowns? Find out how the healing was revealed in unexpected ways.

Oprah sits down with Mike, whose wife suffers from multiple sclerosis and has undergone John of God's 'spiritual surgery.' Did it help? Watch and see.

John of God, one of the world's most famous spiritual healers, shares his beliefs about eternal life, heaven and the power of love. Plus, watch as he reveals his definition of God in just one word and responds to his critics.

While in Brazil, Oprah met several Americans who had traveled thousands of miles to see John of God. Some came searching for spiritual growth, while others were hoping for a medical miracle. Watch as Oprah talks to these followers about their spiritual journeys. Will they still believe in John of God even if he fails to heal them? Find out now.

Do you believe in miracles? Oprah travels to Brazil to visit the world's most famous spiritual healer, John of God. Plus, Oprah gets an up-close look at 'miracle healings,' controversial surgeries performed seemingly without anesthesia or sterilization.

When Chelsea Handler was 21 years old, she was arrested for driving under the influence. During a court-mandated DUI class, Chelsea was required to stand up and explain how she ended up on the wrong side of the law. Find out how Chelsea's hilarious rant about the arrest inspired a career as a stand-up comedian.