Oprah and legendary feminist/activist Gloria Steinem sit down with 60 outspoken students at Barnard College—the most selective women's college in the United States—for a dynamic, provocative and no-holds-barred conversation. Both Gloria and Oprah are asked what price they've paid for their success and if they believe it's possible to really have it all.

Then, Oprah visits Gloria at her bohemian New York City brownstone for an in-depth, one-on-one conversation. Gloria opens up about why she became her mother's caregiver at age 10, marrying at age 66 and the biggest regret of her life.

Oprah travels to Dallas to meet one of the nation's most influential spiritual leaders, Bishop T.D. Jakes. This charismatic leader is the senior pastor of the Potter's House, a global humanitarian organization and 30,000-member church. Oprah's friends Gayle King and Tyler Perry come along for the experience.

Then, Oprah and Bishop Jakes sit down for a provocative conversation about faith, race, ego and love. In this revealing interview, Bishop Jakes opens up about the death of his parents and explains how he became a preacher in his teens. Bishop Jakes' wife, Serita, also talks frankly about the challenges of being married to one of America's most famous preachers. Plus, get a behind-the-scenes look at the 9,000-seat Potter's House and find out how Bishop Jakes' weekly Sunday service comes together.

In an exclusive interview, Oprah goes behind bars at the Orangeburg-Calhoun Regional Detention Center in Orangeburg, South Carolina, to talk to Shaquan Duley, a mother who confessed to murdering her two young sons, 2-year-old Devean and 18-month-old Ja'Van, on August 16, 2010. Although she initially claimed her sons drowned in a car accident, she later confessed to smothering them and then driving them into a river to cover up what she'd done. On March 16, 2012, Shaquan pleaded guilty to two counts of murder and begged for forgiveness from her family, the community and the judge. On March 30, 2012, a judge ordered Shaquan to serve two 35-year sentences concurrently with no chance of parole. She received credit for time served already. Oprah also talks to Shaquan's mother, Helen; her sister, Adriane; and Shaquan's surviving daughter, 7-year-old Saniya.

Oprah spends the day in Fairfield, Iowa—one of the safest, greenest and most unusual communities in America. In the middle of corn country, it's probably the last place you'd expect to find a dome and an evening traffic jam where thousands of the local population of 9,400 are headed to meditate.

Oprah's journey begins at a unique Fairfield school where twice-daily Transcendental Meditation (TM) is a mandatory part of the curriculum. Next, she visits the neighboring community of Maharishi Vedic City—named after the Indian guru who founded the TM movement. Here, nonorganic food is banned, and all houses face east, adhering to an ancient Indian architectural style that is said to bring peace and harmony to one's surroundings. Maharishi Vedic City is also home to a top secret, 80-acre compound where 800 men from India live and spend eight hours a day meditating, chanting and studying. Cameras have never been allowed inside their community—until now.

Later, Oprah joins housewives, engineers, waitresses, lawyers, moms and single ladies at the Golden Dome of Pure Knowledge for evening meditation—a powerful, energizing yet calming experience. Of that experience, Oprah says, "I walked away feeling fuller than when I came in, full of hope and a sense of contentment and deep joy, knowing for sure that in the craziness of the world that seems to bombard us at every angle, there is always the consistency of stillness."

Oprah travels to New York City to give the world its first look inside the apartment Lady Gaga grew up in and still calls home. And for the first time ever, Gaga's mother, Cynthia, breaks her silence on what it's like to be the mom of one of the most famous—and controversial—pop stars on the planet. Oprah tours the living room and sees the spot where Gaga used to practice singing like her idol, Whitney Houston. Gaga also reveals the difficult creative process she goes through each time she writes a new song, and opens up about love, marriage and motherhood. Then, Gaga gives Oprah the inside story of the famous meat dress and her alter ego, Jo Calderone.

Plus, Oprah, Gaga and Cynthia meet up at Harvard University to launch the Born This Way Foundation, Gaga's charitable endeavor—a project that she believes is the most important work of her life.