When baby Kylie is born with birth defects and breathing difficulties, doctors say she won't survive. Can her desperate parents do anything to save her? Then, 17-year-old soccer star Michael Iniguez's sore throat turns into a raging infection that takes over his body. When his vital organs begin failing, Michael's parents rush him to the ER. Can any doctor save Michael before time runs out?

After moving to Michigan to live with her boyfriend, 19-year old Tanya Angus notices some unpleasant changes in her body. The doctors assure her she's perfectly healthy, but Tanya can sense something is wrong. Then sixteen-year old Kody Burns experiences a return of the disabling asthma that overshadowed his pre-teen years. But this time around, there's something very different about his cough.

After Liana Jones's sinus pain leaves doctors baffled, her husband Tom investigates the case in his own lab. Then, single mom Robin Akbar's asthma sends her life into a tailspin.

Matt Horick's hip fails when he is seven years old. An operation repairs the damage, but then a large bump appears on his back. Ruling out cancer, doctors are horrified to discover that Matt's body is actually growing a second skeleton. Then, two-year-old Haven Fowler almost doubles in size in one month. Doctors find and remove a cancerous tumor, but that doesn't stop the problem. Who can help Haven before it's too late?