So it was almost time for Oprah to work her own butt off in her starring debut in Desperate Housewives! It took 200 crew members to help "Karen and Gordon" move into the neighborhood. Take after take, Oprah had plenty of stamina to hang with the pros!
In the special Desperate Housewives' episode for The Oprah Show, Oprah's character, Karen Stouffer, was tired of her stressful job and the demands of running a multi-million dollar corporation. So she and her husband decided to give it all up for a simple life in the suburbs. Unfortunately for Karen, she would soon discover life on Wisteria Lane was anything but simple.