The two CDs (and cassettes) were programmed so that each volume displayed the full range of Whitney's career. Disc 1 (Cool Down), for example, built from her first hits of 1985, "You Give Good Love," "Saving All My Love for You" and "Greatest Love of All," all the way through 2000. Disc 2 (Throw Down) recapped the hits from My Love Is Your Love with club remixes of "It's Not Right But It's Okay," "My Love Is Your Love," "Heartbreak Hotel" and "I Learned from the Best," followed by 10 more hits remixed by Junior Vasquez, David Morales, Jellybean, Hex Hector, C+C Music Factory's Clivilles and Cole and others.
Those remixers were showcased on Whitney: The Unreleased Mixes, a special, limited edition four-record vinyl box set acknowledging her importance in clubs around the world. There were seven songs, eight mixes, one track on each side of four 12-inch vinyl discs: "How Will I Know," "Greatest Love of All," "I'm Every Woman," "Love Will Save the Day," "I Will Always Love You," "So Emotional" and "I'm Your Baby Tonight."
Whitney: The Greatest Hits was also the title of Whitney's first DVD and VHS home video collection. The lion's share of her hits were included in its 21 titles, a combination of video clips (with such noted directors as Wayne Isham, Peter Israelson, Julian Temple, Randee St. Nicholas, Brian Grant and Kevin Bray) and live performances. Links were provided to such rarities as her television premiere (on The Merv Griffin Show in 1985), appearances on several awards show, a tune from Rogers & Hammerstein's Cinderella, interview segments featuring Whitney and her co-producer, Arista president Clive Davis, and much more.
The week after the release of Whitney: The Greatest Hits, she appeared on the NBC television network special benefit concert 25 Years of #1 Hits: Arista Records' Anniversary Celebration, a tribute to the label as well as its founder and leader, Clive Davis.