Even Gayle isn't sure what to do to counteract the side effects of menopause. "I even got the name of a doctor," Gayle says. "But I still can't pick up the phone and call."
Debbie from Missouri wrote to Oprah after learning more about hormones on The Oprah Show.
In the e-mail, she says, "I watched and cried and cried. ... I am 51 and have been going through all that: hot flashes, sleepless nights, fatigue, feeling vulnerable, sad and in general not feeling well every day of my life for the last six years and more. Finally, I feel like I am not crazy or losing my mind."
"You have to do your research and know what you are asking for," Oprah says.
Find out more about hormone replacement therapy