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Mo'Nique and Oprah

This is Mo'Nique's first appearance on The Oprah Show—but it's not the first time she has met Oprah!

In 1978, Oprah became the co-host of People Are Talking, a local talk show in Baltimore. "When you first came on, I had never seen a black woman on television that was a big black woman that looked like me," Mo'Nique says. "I'd never seen that before, and I said, 'I want to do that when I grow up.'"

Mo'Nique says her broadcasting school took a field trip to the set of People Are Talking, where she met Oprah for the first time. "When I put my hand inside of yours, I said, 'You know what? I want to be just like you when I grow up,'" Mo'Nique says. "And you grabbed my hand really tight, and you said, 'You've got to work really hard.' So from one sister to another, I held onto those words for life, and now it's an honor to be sitting here on your stage with you."

"Thank you," Oprah says. "That is so beautiful."

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