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It's open mic day at The Oprah Show! Oprah and her panel of opinionated friends are tackling all the hottest topics—from politics and the economic crisis to pop culture and movie premieres!

In May 2008, Ali Wentworth, Mark Consuelos and Gayle King teamed up with Oprah for the first time. Although Oprah says she couldn't get a word in edgewise during that show, she couldn't wait to do it again!

Ali may be an actress by trade, but at her core, she says she's a mom of two who loves to make mac 'n' cheese and watch The Oprah Show. As the wife of ABC News political analyst George Stephanopoulos, Ali keeps up with the latest headlines...and isn't afraid to share her opinion.

Get to know more about Ali. Watch now! Watch

As a star on All My Children, Mark has made women swoon, but make no mistake—he's a man's man. For the past 12 years, he's learned a thing or two about opinionated women from his wife, talk show host Kelly Ripa. Together, these television stars juggle busy careers and three young children, Michael, Lola and Joaquin.

Get to know more about Mark. Watch now! Watch

You may know Gayle as Oprah's best friend, but what you may not know is that she's also an XM Radio host, the editor-at-large of O, The Oprah Magazine, a mother of two and a self-admitted news junkie. "My background is TV news," she says. "That was and still is my passion. I'm really a TV baby—I love all things television."

Get to know more about Gayle. Watch now! Watch
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FROM: Oprah Fridays: Spike Lee, Ali Wentworth, Mark Consuelos, Gayle King
Published on September 26, 2008

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