13 Shocking Oprah Show Moments

Jacqui Saburido's Story

When she was 19 years old, Jacqui Saburido was hit by a drunk driver in a horrific accident that killed two of her friends and left Jacqui with third-degree burns on nearly 60 percent of her body. After more than 40 surgeries, Jacqui remained disfigured but appeared on The Oprah Show on November 25, 2003, to share her struggle, strength and inspiration.

"[She is] a woman who defines 'survival'," Oprah said.