In 25 years, some of The Oprah Winfrey Show's most memorable moments happened away from Chicago's Harpo Studios.
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Union, South Carolina
Susan Smith made headlines—first for pleading with the man she said abducted her two young sons Michael, 3, and Alexander, 14 months, to bring them home, then for confessing she had killed them by pushing the family car into a lake with the boys inside. In 1994, Oprah traveled to the scene of the crime to find out how something so horrific could happen.