While some Skypers use the software to build personal relationships, others log on for professional reasons. With millions of clients at her fingertips, Barbara, an artist from Toronto, Canada, has developed a new medium and broadened her business. She calls herself a "Skype sketcher."

Barbara takes photos of people through Skype and then uses these images to create their portraits. "I can go to people all over the world and sketch them," she says. "It's a brand new portrait format, and I just love it."

In just 45 minutes, Barbara turns a photo of Oprah into a portrait. "Thank you so much," Oprah says. "I am loving myself."