Five minutes into the drive, Gayle's already singing (just like she did on their road trip). While Gayle sings along to Toby Beau's "Angel Baby," Oprah puts on her earphones, which she says "drown out everything."
Look back on Oprah and Gayle's big adventure across the country!
Best friends Oprah and Gayle look back on 25 years of special moments shared on The Oprah Show.
An audience of 300 Oprah Show Ultimate Viewers get the surprise of a lifetime! Plus, find out which special celebrity guests drop by and watch a surprise musical performance.
See what happens when Oprah and Gayle go camping at Yosemite National Park.