Photo: Paramount Pictures/Photofest

In one 1970 photograph, Ali and Ryan are two young actors, on the verge of becoming household names.

Oprah: What would you say to your young self there, Ryan?

Ryan: What would I say to him? "Lucky boy."

Oprah: What would you say to your young self, knowing what you know now, Ali?

Ali: "Oh, heaven help you."