While Dr. Burke's hospitalization shocked fans, it also struck a personal chord with Isaiah. He says the finale reminded him of his own mother's real-life battle with sarcoidosis, a lung disease that took her life. "At one point, watching her make her 'transition' in a hospital—I swore that I would never walk into another hospital again," Isaiah says.
Luckily for viewers, Isaiah did step into a hospital again in what has been an empowering role for the actor. "I love Dr. Burke," he says. "Dr. Burke is my hero."