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George Clooney

Oprah wants to know—does George focus on the box office and does he hope to leave a legacy other than box-office blowouts?

"Movies like It's a Wonderful Life were big [box office] flops," George says, "so I find that you don't concern yourself necessarily with the box office. Out of Sight didn't make any money and it's a really good film, and O Brother, Where Art Thou? didn't really make much money and it's a really good film. … I think you want people that you know to be proud of you. You want to do stuff that you're proud of that lasts longer than an opening weekend."

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