Brad Pitt and Cate Blanchett

When Brad Pitt hit the big screen as a sweet-talking hitchhiker armed with six-pack abs and a hairdryer in Thelma & Louise, he was catapulted to movie star status. Brad went on to make his blockbuster debut in 1994 starring alongside Tom Cruise and an 11-year-old Kirsten Dunst in Interview with a Vampire. That same year, Brad smoldered onscreen as Tristan in the epic Legends of the Fall. He followed with a series of quirky and intense films like Fight Club, Se7en, Snatch and his Oscar®-nominated role in Twelve Monkeys.

By 2004, Brad was cast in a classic Hollywood leading man role as Achilles in the Greek epic Troy. Brad then met his real-life love, Angelina Jolie, in the action-packed, tongue-in-cheek Mr. and Mrs. Smith. But Brad still knows how to have fun—he and his Ocean's buddies always deliver.

"It's been four long years since I've uttered these words, and they are sure to make this audience very happy," Oprah says. "Brad Pitt is here!"