In a small heavy gauge sauce pot, combine sugar and Karo syrup, stir in water until the mixture resembles wet sand.
Cook, without stirring, over medium heat until mixture is amber in color.
Once desired color is achieved, remove from heat and whisk in butter (until completely melted), then warm heavy cream and vanilla.
Be careful when adding cream as steam and bubbles will rise. Cool and serve on top of Easy Monkey Bread.