Monica Jorge, a wife and mother of two daughters, shares what a typical day is like in her home after losing her arms and legs to deadly flesh-eating bacteria. Plus, she talks about some of the physical obstacles she faces.

She survived drastic surgery and flesh-eating bacteria. Watch as Tanya learns to live with one arm.

Oprah and Gayle King sit down to talk about what, for Oprah, is the biggest change in 25 years: the end of The Oprah Winfrey Show.

Jo Ann Compton's tragic loss made her one of Oprah's most memorable guests. See how she's doing today.

Oprah surprises Denni Foster, a single mom working multiple jobs to support her family, with the mother of all paydays!