17 Headline-Making Moments on The Oprah Show

Texas Cattlemen v. Oprah—1998

After a guest on an episode of The Oprah Show made a comment about tainted beef and Mad Cow Disease, a trade group of Texas beef producers filed a defamation suit against Oprah. Instead of shutting down during the trial, Oprah brought her show on the road. She taped The Oprah Show for more than a month in 1998 in Amarillo, Texas, spending her days in court and her nights in the studio. "It was one of the most stressful times I've ever personally experienced," Oprah said.

Oprah says her friendships with Celine Dion, Halle Berry and John Travolta strengthened during the trial, which she won. "That trial was one of the most significant life-changing moments," Oprah says.