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17 Headline-Making Moments on The Oprah Show

In 25 seasons, The Oprah Show has taken on some of the biggest stories of our time.
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Oprah and Elizabeth Edwards

Elizabeth Edwards Exclusive—2009

In 2009, Oprah sat down for the exclusive first interview with Elizabeth Edwards after husband, former Democratic vice presidential nominee John Edwards, went public with news that he'd had an affair with another woman.

A year later, Oprah sat down with Rielle Hunter—John Edwards' "other woman"—for a candid one-on-one interview

Published on April 14, 2011
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