Oprah and the ultimate viewers who each lost over 100 pounds hide their slim figures behind their former "fat" clothes, May 10, 2011.
Best friends Oprah and Gayle look back on 25 years of special moments shared on The Oprah Show.
The Oprah Show looks back at 25 years of gay issues featured on the show.
Oprah talks about upcoming shows on her new cable network, OWN: The Oprah Winfrey Network.
OWN offers sneak peek at upcoming shows in development at the new cable network, including Dr. Laura Berman, Peter Walsh, Lisa Ling, Ashton Kutcher and more.
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